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Animal Health

 

Salmonella enterica Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid and insulin/mTOR signaling

 

Ryan J Arsenault, Scott Napper and Michael H Kogut

 

 

Salmonella enteric serovar Typhimurium (Salmonella Typhimurium) infection of chickens that are more than a few days old results in asymptomatic cecal colonization with persistent shedding of bacteria. We hypothesized that while the bacterium colonizes and persists locally in the cecum it has systemic effects, including changes to metabolic pathways of skeletal muscle, influencing the physiology of the avian host. This is the first report of significant cellular metabolic changes occurring systemically in chicken due to a Salmonella infection.

 

 

For more of the article, please click here.

 
Article made possible through the contribution of Ryan J. Arsenault et. Al. and Biomed Central.

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