Genotype imputation accuracy in a F2 pig population using high density and low density SNP panels
F2 resource populations have been used extensively to map QTL segregating between pig breeds. A limitation associated with the use of these resource populations for fine mapping of QTL is the reduced number of founding individuals and recombinations of founding haplotypes occurring in the population. These limitations, however, become advantageous when attempting to impute unobserved genotypes using within family segregation information.
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Article made possible through the contribution of Jose L G. Duarte et. Al. and Biomed Central.