Stress induced Salmonella Typhimurium recrudescence in pigs coincides with cortisol induced increased intracellular proliferation in macrophages
Salmonella Typhimurium infections in pigs often result in the development of carriers that intermittently excrete Salmonella in very low numbers. During periods of stress, for example transport to the slaughterhouse, recrudescence of Salmonella may occur, but the mechanism of this stress related recrudescence is poorly understood. Therefore, the aim of the present study was to determine the role of the stress hormone cortisol in Salmonella recrudescence by pigs.
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Article made possible through the contribution of Elin Verbrugghe, Filip Boyen, Alexander Van Parys, Kim Van Deun, Siska Croubels, Arthur Thompson, Neil Shearer, Bregje Leyman, Freddy Haesebrouck, Frank Pasmans and BioMed Central.