Some aspects of purinergic signaling in the ventricular system of porcine brain
Numerous signaling pathways function in the brain ventricular system, including the most important - GABAergic, glutaminergic and dopaminergic signaling. Purinergic signalization system - comprising nucleotide receptors, nucleotidases, ATP and adenosine and their degradation products -are also present in the brain. However, the precise role of nucleotide signalling pathway in the ventricular system has been not elucidated so far. The aim of our research was the identification of all three elements of purinergic signalling pathway in the porcine brain ventricular system.
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Article made possible through the contribution of Joanna Czarnecka, Katarzyna Roszek, Artur JabÅ‚oÅ„ski, Dariusz Jan SmoliÅ„ski, Michal KomoszyÅ„ski and BioMed Central.