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Animal Health
Thursday, February 28, 2013 4:30:38 PM
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Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle - an update

 
Timm Konold, Mark E Arnold, Anthony R Austin, Saira Cawthraw, Steve AC Hawkins, Michael J Stack, Marion M Simmons, A Robin Sayers, Michael Dawson, John W Wilesmith and Gerald AH Wells
 


This updated research provide information on dose-response and aid in modelling the exposure dynamics of the BSE epidemic in the United Kingdom groups of cattle were exposed orally to a range of different doses of brainstem homogenate of known infectious titre from clinical cases of classical bovine spongiform encephalopathy (BSE).


Interim data from this study was published in 2007. This communication documents additional BSE cases, which occurred subsequently, examines possible influence of the bovine prion protein gene on disease incidence and revises estimates of effective oral exposure.

 


For more of the article, please click here.
 
Article made possible through the contribution of Konold et. al. and Biomed Central.
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